Brook Tilahun

Brook Tilahun

Computational Biology Scientist

Genovac

I am a scientist working at an antibody discovery company, where I apply machine learning and AI approaches to accelerate in silico antibody discovery and protein engineering.

My work focuses on leveraging protein language models, structure prediction tools, and ML pipelines to identify and engineer therapeutic antibody candidates.

This site showcases my research projects, technical skills, and thoughts on applied ML in biologics discovery.

I believe in the power of collaboration. If you see an opportunity for us to work together or need support, please reach out.

Interests
  • Generative AI for Antibody/Protein Design
  • Protein Structure Prediction
  • Machine Learning for Therapeutic Discovery
  • Multi-omics Data Integration
  • Bioinformatics & NGS Analysis
Education
  • Bachelor's in Neuroscience, Data Science and Psychology

    Concordia College

Technical Skills

Python
Machine Learning
Protein Structure Prediction
Bioinformatics
Data Science
R

Experience

 
 
 
 
 
Genovac
Scientist I
Genovac
July 2025 – Present Fargo, ND

I build diffusion-based pipelines for de novo antibody sequence design and custom ML tools for predicting affinity, stability, and manufacturability from proprietary wet lab data. The work is about turning model outputs into testable hypotheses for the bench team.

diffusion models structure-function modeling antibody engineering PyTorch HPC

 
 
 
 
 
Genovac
Associate Scientist II
Genovac
March 2024 – July 2025 Fargo, ND

Built a deep learning humanization platform for optimizing mouse-derived lead candidates and led the onboarding of Oxford Nanopore sequencing infrastructure, including the downstream analysis workflows.

antibody humanization deep learning PLM NGS pipelines

 
 
 
 
 
Aldevron
QA Data Specialist 2
Aldevron
January 2023 – March 2024 Fargo, ND

Built data pipelines from production databases to identify manufacturing bottlenecks and reduce turnaround times for gene therapy products. Got a thorough look at GMP environments and the quality standards that govern therapeutics.

data pipelines gene therapy GMP manufacturing

 
 
 
 
 
Harvard Medical School, Beth Israel Deaconess Medical Center
Research Intern
Harvard Medical School, Beth Israel Deaconess Medical Center
May 2022 – March 2023 Boston, MA

Transcriptomic analysis on Nanopore RNA-seq data and image analysis pipelines in ImageJ for characterizing microglial morphology. Contributed to work published in Cell Reports Medicine.

RNA-seq analysis Nanopore Sequencing cloud compute ImageJ neuroimmunology

 
 
 
 
 
Concordia College
Student Researcher
Concordia College
June 2021 – May 2022 Moorhead, MN

Designed zebrafish behavioral enrichment experiments, performed gene enrichment analysis in R, and presented at multiple academic conferences.

behavioral neuroscience R gene enrichment zebrafish anatomy

Certificates

Coursera
Genomic Data Science Specialization by John’s Hopkins University
See certificate
Coursera
Data Analytics Specialization by Google
See certificate

Recent Posts

Projects

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Zebrafish enrichment analysis
Experiment summary of my undergraduate research internship at Concordia college.
Zebrafish enrichment analysis
Decoding Heart Disease, A Comprehensive Data Analysis
A project demonstrating and comparing the predictive abilities of different ML models in associating different measures to heart disease
Decoding Heart Disease, A Comprehensive Data Analysis
Lupus Mice Model
Experiment summary of my undergraduate research internship at Concordia college.
Lupus Mice Model

Contact

Feel free to contact me via email or LinkedIn.